Association of poor insight in schizophrenia with structure and function of cortical midline structures and frontopolar cortex

Schizophrenia Research, 06/11/2012

The findings suggest a link between known regional brain abnormalities and the manifestation of poor insight in schizophrenia. The contribution of cortical midline structures to insight may be related to self–referential processing and that of frontopolar cortex to the integration of multiple cognitive processes that are necessary for accurate evaluation of one's mental illness.

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