Midlife vs Late-Life Depressive Symptoms and Risk of Dementia: Differential Effects for Alzheimer Disease and Vascular Dementia

JAMA Psychiatry, 05/09/2012

Depressive symptoms in midlife or in late life are associated with an increased risk of developing dementia. Depression that begins in late life may be part of the Alzheimer disease prodrome, while recurrent depression may be etiologically associated with increased risk of vascular dementia.

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