Ovarian morphology in premenstrual dysphoria

Psychoneuroendocrinology, 05/01/2012

Serum free testosterone levels in late premenstrual phase showed an inverse association to premenstrual symptoms of irritability and a similar inverse association trend to symptoms of depressed mood. Unexpectedly, the prevalence of ovaries with fewer than five antral or growing follicles was significantly higher in women with premenstrual dysphoria than in controls. The results do not support a role for polycystic ovaries or androgen hormones in eliciting late luteal phase irritability.

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