The impact of mood, anxiety, and sleep disorders on fibromyalgia

Comprehensive Psychiatry, 04/30/2012

Psychiatric comorbidity, in particular with mood disorders, provokes a significant impairment of the health–related quality of life and, when current, a higher severity of pain in fibromyalgia patients.


  • One-hundred and sixty-seven women suffering from primary FM were consecutively enrolled.
  • Psychiatric diagnoses were made by means of DSM-IV criteria.
  • The HRQoL and the severity of pain were measured through the Medical Outcomes Study 36-item Short-Form Health Survey (MOS-SF-36) and the FM Impact Questionnaire (FIQ).


  • Fibromyalgia patients showed a high rate (80.8%) of lifetime and/or current comorbidity with mood and anxiety disorders.
  • Patients with psychiatric comorbidity resulted significantly more impaired on the Mental Component Summary score of the MOS-SF-36 and showed a higher FIQ total score than those suffering from FM only.
  • The severity of pain was associated with current psychiatric comorbidity.
  • Patients with current mood disorders showed significantly lower Mental and Physical Component Summary scores of the MOS-SF-36 and higher FIQ total scores than those with current anxiety disorders or those without psychiatric comorbidity.
  • Finally, patients with sleep disorders reported a lower HRQoL than those with a normal sleep, and specifically those with difficulty in falling in sleep had higher severity of pain.

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