Frequency and predictors of proxy-confirmed post-stroke cognitive complaints in lacunar stroke patients without major depression
International Journal of Geriatric Psychiatry, 01/07/2011
Xiong YY et al. – Many lacunar stroke patients complained of cognitive decline after stroke. This study aims to investigate the factors underlying post-stroke cognitive complaints in these patients. This study suggests that post-stroke cognitive complaints are frequent among lacunar stroke patients without major depression and are prominently determined by the subclinical depressive symptomatology.
75 consecutive lacunar stroke patients without major depression were recruited for study
Stroke severity measured using NIHSS score and MRI performed during acute admission period
At 3 months, objective psychometric performance and depressive symptoms assessed
Post-stroke cognitive complaints corroborated by proxy
Using logistic regression examined contribution of demographic features, stroke severity, objective psychometric scores, depressive symptoms, and imaging features (white matter lesion volume and infarct measures) to post-stroke cognitive complaints
Thirty-two (42.7%) patients had post-stroke cognitive complaints
Patients with post-stroke cognitive complaints had more depressive symptoms and worse psychometric performance than those without
In multivariate logistic regression model, only severity of depressive symptoms independently associated with post-stroke cognitive complaints
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