Measured physical activity in anorexia nervosa: features and treatment outcome
International Journal of Eating Disorders, June 6, 2013
El Ghoch M et al. – The study aims to assess the role of measured physical activity (PA) in anorexia nervosa treatment outcome, and to compare the PA of patients with anorexia nervosa with age–matched controls. PA is higher in patients with anorexia nervosa than age–matched controls both before and after treatment, and is associated with treatment dropout.
PA was assessed by means of Sense Wear Armband before and after a cognitive-behavioral inpatient treatment in 53 ...
Subcallosal cingulate deep brain stimulation for treatment-refractory anorexia nervosa: a phase 1 pilot trial
The Lancet, March 14, 2013
Lipsman N et al. - Anorexia nervosa is characterised by a chronic course that is refractory to treatment in many patients and has one of the highest mortality rates of any psychiatric disorder. Deep brain stimulation (DBS) has been applied to circuit-based neuropsychiatric diseases, such as Parkinson's disease and major depression, with promising results. Authors aimed to assess the safety of DBS to modulate the activity of limbic circuits and to examine how this might affect the ...
Drop-out and treatment outcome of outpatient cognitive-behavioral therapy for anorexia nervosa and bulimia nervosa
Comprehensive Psychiatry, April 16, 2013
Schnicker K et al. - In the present study, drop-out-analyses were carried out for a manual-based cognitive–behavioral therapy for 104 females with anorexia nervosa (AN) and bulimia nervosa (BN), in the service setting of a university outpatient clinic (naturalistic setting). For patients with AN, even higher therapy effects were observed among the drop-outs than among the completers. The data suggest that moderate therapy effects and responses can be achieved even ...
A history of the identification of the characteristic eating disturbances of Bulimia Nervosa, Binge Eating Disorder and Anorexia Nervosa
Appetite, March 27, 2013
Heaner MK et al. - During the last 25years, the careful examination of the eating behavior of individuals with eating disorders has provided critical insights into the nature of these disorders. Crucially, studies investigating components of different eating behaviors have documented that Anorexia nervosa (AN), Bulimia nervosa (BN), and Binge Eating Disorder (BED) are characterized by objective disturbances in eating patterns that are significantly different than behaviors exhibited by ...
Factors associated with recovery from anorexia nervosa
Journal of Psychiatric Research, March 28, 2013
Zerwas S et al. - This retrospective study examined the association between prognostic factors—eating disorder features, personality traits, and psychiatric comorbidity—and likelihood of recovery in a large sample of women with anorexia nervosa (AN) participating in a multi-site genetic study. There was a significant interaction between impulsivity and time; the association between impulsivity and likelihood of recovery decreased as duration of AN increased. The anxiolytic function ...
Quality of Life in Anorexia Nervosa: A Review of the Literature
Eating Disorders, April 23, 2013
Sy R et al. - The aim of this study was to compare quality of life in anorexia nervosa patients to that of subjects without eating disorders, with other eating disorders, or with other psychiatric disorders. Results showed reduced quality of life for eating disorder patients, including anorexia nervosa, as compared to normal controls and individuals with other psychiatric disorders; however, whether anorexia nervosa treatment resulted in improved quality of life remains controversial.
The MOSAIC study - comparison of the Maudsley Model of Treatment for Adults with Anorexia Nervosa (MANTRA) with Specialist Supportive Clinical Management (SSCM) in outpatients with anorexia nervosa or eating disorder not otherwise specified, anorexia nervosa type: study protocol for a randomized controlled trial
Trials, June 12, 2013
Schmidt U et al. - The aim of the Maudsley Outpatient Study of Treatments for Anorexia nervosa and Related Conditions (MOSAIC) is to evaluate the efficacy and cost effectiveness of two outpatient treatments for adults with AN, Specialist Supportive Clinical Management (SSCM) and the Maudsley Model of Treatment for Adults with Anorexia nervosa (MANTRA). This multi-center study provides a large sample size, broad inclusion criteria and a follow-up period. However, the study has ...
Refeeding Hypophosphatemia in Adolescents With Anorexia Nervosa: A Systematic Review
Nutrition in Clinical Practice, March 6, 2013
O’Connor G et al. - This review sought to identify the range of refeeding rates adopted globally and the implication that total energy intake and malnutrition may have on Refeeding hypophosphatemia (RH) while refeeding adolescents with anorexia nervosa. This review highlights the disparity in refeeding rates adopted internationally in treating malnourished adolescents with anorexia nervosa. Based on this review, the severity of malnutrition seems to be a marker for the development of RH ...
The study of candidate genes related to the neurodevelopmental hypothesis of anorexia nervosa: Classical association study versus decision tree
Psychiatry Research, March 19, 2013
Dmitrzak-Weglarz M et al. - In this research, the authors conducted a study of genes connected with the neurodevelopmental hypothesis of anorexia nervosa, using classical statistical and data-mining methods to establish a relationship with disease risk and algorithms to identify the best genetic predictors of anorexia nervosa.
Two diagnoses become one- Rare case report of anorexia nervosa and Cushing’s syndrome
Neuropsychiatric Disease and Treatment, April 4, 2013
Sawicka N et al. - The authors report a patient diagnosed with anorexia nervosa who also developed Cushing’s syndrome. A 26-year-old female had been treated for anorexia nervosa since she was 17 years old, and also developed depression and paranoid schizophrenia. She was admitted to the Department of Endocrinology, Metabolism, and Internal Medicine with a preliminary diagnosis of Cushing’s syndrome. Computed tomography revealed a 27 mm left adrenal tumor, and she underwent ...