1Efficacy and safety of pharmacological and psychological interventions for the treatment of psychosis and schizophrenia in children, adolescents and young adults: a systematic review and meta-analysisPLOS ONE  Evidence Based Medicine  Review Article
2Do depressed newly diagnosed cancer patients differentially benefit from nurse navigation?General Hospital Psychiatry  Clinical Article
3Unhealthy lifestyle may increase later depression via inflammation in older women but not menJournal of Psychiatric Research  Clinical Article
4The facts about sexual (dys)function in schizophrenia: An overview of clinically relevant findingsSchizophrenia Bulletin  Clinical Article
5Depression and anxiety symptoms of mothers of preterm infants are decreased at 4 months corrected age with Family Nurture Intervention in the NICUArchives of Women's Mental Health  Clinical Article
6Overview of antidepressant treatment of bipolar depressionFOCUS  Review Article
7Social responsiveness, an autism endophenotype: Genomewide significant linkage to two regions on chromosome 8American Journal of Psychiatry  Clinical Article
8Understanding responder neurobiology in schizophrenia using a quantitative systems pharmacology model: Application to iloperidoneJournal of Psychopharmacology  Clinical Article
9An exploratory short-term double-blind randomized trial of varenicline versus nicotine patch for smoking cessation in womenAddiction  Clinical Article
10Treatment with anti-toxoplasmic activity (TATA) for Toxoplasma positive patients with bipolar disorders or schizophrenia: A cross-sectional studyJournal of Psychiatric Research  Clinical Article
1Study reveals mechanism behind most common form of inherited Alzheimer's diseaseMassachusetts General Hospital
2Raising tobacco sales age to 21 is best way to prevent lifelong addictionOhio State University News
3Medicare and patients with schizophrenia could save $150 million on part D plansUPMC
4Stigma of mental illness in India linked to povertyWashington University School of Medicine in St. Louis News
5Mental health soon after war-zone concussions predicts disabilityWashington University School of Medicine in St. Louis News
6Study offers clues to early detection of bipolar disorders in high-risk childrenNationwide Children's Hospital
7Twitter helps smokers kick the habit, UCI-Stanford study findsUniversity of California Irvine Health News
8Marijuana: The allergen you never knew existedAmerican College of Allergy, Asthma and Immunology News
9Scripps Florida scientists find a defect responsible for memory impairment in agingScripps Research Institute News
10Time to "just say no" to behavior-calming drugs for Alzheimer patients? Experts say yesUniversity of Michigan Health System

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Risk factors for suicidal ideations in bipolar disorder

As reported in Bipolar Disorders, the following risk factors were associated with suicidal ideations in patients with bipolar disorder (n=130): grade of severity of current episode (OR=22.601); family history of suicide attempt (OR=18.06); preceding life event (OR=3.797); and past history of suicidal event (OR=3.11).

Salivary markers for alcohol dependence identified

As reported in Alcohol & Alcoholism, salivary levels of α-fucosidase, β-glucuronidase, and α-mannosidase are elevated (7-18-fold) in patients with alcohol dependence compared to healthy controls.

Children’s Depression Screener is a useful tool

As reported in Psychiatry Research, the Children’s Depression Screener (ChilD-S) has been shown to have a diagnostic accuracy of 0.97 in children with depression and at a cut-off level ≥ 12, the sensitivity and specificity are 0.91 and 0.81, respectively.

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Clinical Pearls

Clinical Pearl from Smartest DocSocial anxiety disorder and antisocial personality disorder appear to be two separate but correlated disorders.

Clinical Pearl from Smartest DocHigher serum DHEAS levels are protective against the onset of depression.

Clinical Pearl from Smartest DocNegative spiritual coping is related to more externalizing and internalizing problems in adolescents with cystic fibrosis

The Top Read Articles of 2014 are Now Available

Scouring thousands of peer-reviewed journals and popular press, Our Editors just released the Top Read Articles of the Year. See the Top Read List