We have Ranked, Sorted and Summarized the Latest Clinical Articles.

1Functional outcomes from a head-to-head, randomized, double-blind trial of lisdexamfetamine dimesylate and atomoxetine in children and adolescents with attention-deficit/hyperactivity disorder and an inadequate response to methylphenidateEuropean Child and Adolescent Psychiatry, May 27, 2015  Clinical Article
2Does lithium reduce acute suicidal ideation and behavior?: A protocol for a randomized, placebo-controlled multicenter trial of lithium plus Treatment As Usual (TAU) in patients with suicidal major depressive episodeBMC Psychiatry, May 27, 2015  Full Text  Clinical Article
3Psychological factors at early stage of treatment as predictors of receiving chemotherapy at the end of lifePsycho-Oncology, May 27, 2015  Clinical Article
4Feasibility and effectiveness of a multi-element psychosocial intervention for first-episode psychosis: Results from the cluster-randomized controlled GET UP PIANO Trial in a catchment area of 10 million inhabitantsSchizophrenia Bulletin, May 27, 2015  Clinical Article
5Profile of agomelatine and its potential in the treatment of generalized anxiety disorderNeuropsychiatric Disease and Treatment, May 27, 2015  Full Text  Review Article
6Validation of the “rule of three”, the “red sign” and temperament as behavioral markers of bipolar spectrum disorders in a large sampleJournal of Affective Disorders, May 27, 2015  Clinical Article
7Can computer-assisted cognitive remediation improve employment and productivity outcomes of patients with severe mental illness?: A meta-analysis of prospective controlled trialsJournal of Psychiatric Research, May 27, 2015  Evidence Based Medicine
8Altered prefrontal cortex activity during working memory task in bipolar disorder: A functional magnetic resonance imaging study in euthymic bipolar I and II patientsJournal of Affective Disorders, May 27, 2015  Clinical Article
9Decreased regional activity and network homogeneity of the fronto-limbic network at rest in drug-naive major depressive disorderAustralian and New Zealand Journal of Psychiatry, May 27, 2015  Clinical Article
10Cross-cultural approach of postpartum depression: Manifestation, practices applied, risk factors and therapeutic interventionsPsychiatric Quarterly, May 27, 2015  Review Article

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We have Ranked, Sorted and Summarized the Latest Clinical Articles.

1Researchers identify mechanisms linking early adversity, disease later in lifeUniversity of Georgia Research News, May 27, 2015
2Towards a better understanding of depressionMcGill University News, May 27, 2015
3Subconscious learning shapes pain responsesKarolinska Institutet, May 27, 2015
4How a schizophrenia risk gene affects the brainLancaster University News, May 27, 2015
5Smokers don't vote: 11,626-person study shows marginalization of tobacco usersUniversity of Colorado Health News, May 26, 2015
6Persistent nightmares in childhood could be linked to psychotic experiences in later adolescenceUniversity of Warwick Health and Medicine News, May 26, 2015
7Home-brewed opiates serious public health concernUniversity of Alberta Faculty of Medicine & Dentistry News, May 26, 2015
8Fine particulate air pollution associated with increased risk of childhood autismUPMC, May 26, 2015
9Towards a better understanding of the mechanisms of depressionDouglas Mental Health University Institute News, May 26, 2015
10Five Indiana health centers join initiative to combat alcohol and substance abuseIndiana University Bloomington Health Sciences News, May 26, 2015

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Children’s Depression Screener is a useful tool

As reported in Psychiatry Research, the Children’s Depression Screener (ChilD-S) has been shown to have a diagnostic accuracy of 0.97 in children with depression and at a cut-off level ≥ 12, the sensitivity and specificity are 0.91 and 0.81, respectively.

Risk factors for suicidal ideations in bipolar disorder

As reported in Bipolar Disorders, the following risk factors were associated with suicidal ideations in patients with bipolar disorder (n=130): grade of severity of current episode (OR=22.601); family history of suicide attempt (OR=18.06); preceding life event (OR=3.797); and past history of suicidal event (OR=3.11).

Psychomotor speed predicts social function in schizophrenics

As reported in the Nordic Journal of Psychiatry, slow psychomotor speed predicts poor 5-y social function (OR=3.37) in patients with a diagnosis of schizophrenia spectrum. Global cognitive function and verbal learning ability had no association with subsequent social function.

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Clinical Pearls

Clinical Pearl from Smartest DocGeneral practitioners have a different perspective on depression diagnosis than does the Geriatric Depression Scale.

Clinical Pearl from Smartest DocAdjunctive pioglitazone is effective for improving depressive symptoms in bipolar disorder without type 2 diabetes or metabolic syndrome.

Clinical Pearl from Smartest DocThe population of older patients with schizophrenia is increasing, as are their comorbidities.

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