Red Blood Cell Transfusion and Transfusion Alternatives in Traumatic Brain Injury
Current Treatment Options in Neurology, 03/05/2012
Kramer AH et al. – Erythropoietin is currently of great interest as a potential neuroprotective agent, but until it is adequately evaluated in randomized controlled trials, it should not be used routinely for this purpose. Hemoglobin–based blood substitutes (HBBSs) are also of interest, but existing preparations have not been shown to be beneficial—or even safe—in the context of traumatic brain injury (TBI).