Derivation and Validation of a Cytokine-Based Assay to Screen for Acute Rejection in Renal Transplant Recipients Clinical Journal of the American Society of Nephrology, 06/12/2012

De Serres SA et al. – Secondary analyses revealed a strong association between IL–6 levels and acute rejection after multivariate adjustment for clinical characteristics. In this pilot study, the measurement of a single cytokine can exclude acute rejection with a sensitivity of 92% in renal transplant recipients presenting with acute graft dysfunction.

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