Improved Working Memory Following Novel Combinations of Physical and Cognitive Activity Neurorehabilitation and Neural Repair, 05/18/2012

Langdon KD et al. – A novel combination of physical activity (PA) and cognitive activity (CA) improves learning and memory abilities independent of activity intensity, brain–derived neurotrophic factor (BDNF), or phosphorylated cyclic AMP response element binding protein levels. This is the first report of significant changes in cognitive ability using a paradigm involving moderate levels of PA plus cognitive stimulation. An adaptation of this paradigm may be particularly beneficial in slowing the development of mild cognitive impairment and subsequent dementia in elderly people.

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