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Physician Assistant - Hematology/Oncology News & Articles

The Medical Editors at MDLinx.com diligently work around the clock to provide the most current Physician Assistant medical news articles from over 2,000 peer-reviewed clinical journals. Our coverage includes over 32 specialties and 800 subspecialties, perfect for the multidisciplinary practice of today’s PAs. Topics include: everything from Anesthesiology to Women’s Health, plus Economics of Medicine, Popular Press, Teaching Hospital News, and much more. In less than 5 minutes a day, Physician Assistants can be updated with the latest published information from thousands of journals after consulting just one resource.

Read on to find exclusive content highly recommended by our Senior Editor, D. Scott Cunningham, MD, PhD, along with clinical pearls from the Smartest Doc , a daily quiz competition now available in 10 specialties.

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Articles

Latest (27) Full Text Articles (1655)
Ranked, sorted, and summarized by MDLinx editors from the latest literature
Topics:

1 Results of initial low-dose computed tomographic screening for lung cancer New England Journal of Medicine, May 24, 2013    Evidence Based Medicine    Clinical Article

2 Noninvasive detection of her2 amplification with plasma dna digital pcr Clinical Cancer Research, May 24, 2013    Review Article

3 VEGF-C and VEGF-D blockade inhibits inflammatory skin carcinogenesis Cancer Research, May 24, 2013    Review Article

4 Phase II trial of panobinostat, an oral pan-deacetylase inhibitor in patients with primary myelofibrosis, post-essential thrombocythaemia, and post-polycythaemia vera myelofibrosis British Journal of Haematology, May 24, 2013    Clinical Article

5 Prognostic interest in discriminating muscularis mucosa invasion (t1a vs t1b) in nonmuscle invasive bladder carcinoma: french national multicenter study with central pathology review The Journal of Urology, May 24, 2013    Clinical Article

6 Pseudocarcinomatous urothelial hyperplasia of the bladder: clinical findings and followup of 70 patients The Journal of Urology, May 24, 2013    Review Article

7 Histone demethylase KDM4C regulates sphere formation by mediating the crosstalk between Wnt and Notch pathways in colonic cancer cells Carcinogenesis, May 24, 2013    Review Article

8 Nanog expression is negatively regulated by protein kinase C activities in human cancer cell lines Carcinogenesis, May 24, 2013    Review Article

9 The impact of coffee on health Maturitas, May 24, 2013    Clinical Article

10 Induction chemotherapy for squamous cell head and neck cancer Oral Oncology , May 24, 2013    Review Article

11 Helicobacter pylori infection and normal colorectal mucosa - adenomatous polyp - adenocarcinoma sequence: a meta-analysis of 27 case-control studies Colorectal Disease, May 24, 2013    Clinical Article

12 Recent advances in the treatment of metastatic renal cell carcinoma International Journal of Urology, May 24, 2013    Clinical Article

13 Novel antibodies targeting immune regulatory checkpoints for cancer therapy British Journal of Clinical Pharmacology, May 24, 2013    Review Article

14 Differences in prostate cancer detection rates according to the level of glomerular filtration rate in patients with prostate specific antigen levels of 4.0-10.0 ng/ml International Journal of Clinical Practice, May 24, 2013    Clinical Article

15 Patient demographics, quality of life, and disease features of men with newly diagnosed prostate cancer: trends in the PSA era Urology, May 24, 2013    Clinical Article

16 A phase II trial of neoadjuvant nab-paclitaxel, carboplatin, and gemcitabine (ACAG) in patients with locally advanced carcinoma of the bladder Urology, May 24, 2013    Clinical Article

17 Clinical factors predicting the response of acute graft-versus-host disease to corticosteroid therapy: an analysis from the GVHD working group of the Japan Society for Hematopoietic Cell Transplantation Biology of Blood and Marrow Transplantation, May 24, 2013    Clinical Article

18 Curcumin acts anti-proliferative and pro-apoptotic in human meningiomas Journal of Neuro-Oncology, May 24, 2013    Clinical Article

19 Diagnosing cancer in the bush: a mixed methods study of GP and specialist diagnostic intervals in rural Western Australia Family Practice, May 24, 2013    Review Article

20 Evaluation of the effect of blackcurrant products on gut microbiota and on markers of risk for colon cancer in humans Phytotherapy Research, May 24, 2013    Clinical Article

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Clinical Pearls in Physician Assistant

Highlights in Physician Assistant

Statins do not increase risk of malignant melanoma in postmenopausal women

In a study headed by researchers at Wayne State University involving 119,726 postmenopausal women enrolled in the Women’s Health Initiative, there were 1099 incident cases of malignant melanoma over an average follow-up of 11.6 y. At the time of enrollment, 7.4% of the participants used statins. The annualized rate of malignant melanoma in the statin users and non-users was 0.09% (HR=1.14). Thus, statin use does not increase the risk of malignant melanoma in postmenopausal women.

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Simple, safe, effective, low-cost treatment for cancer-related anorexia/cachexia syndrome

A phase III trial conducted at the University of Cagliari showed that either of two regimens were effective in the treatment of cancer-related anorexia/cachexia syndrome (CACS). Sixty patients were randomized to receive one of the following treatment interventions for 4 months: 1) L-carnitine (4 g/d) + celecoxib (300 mg/d); or 2) L-carnitine + celecoxib + megestrol acetate (320 mg/d). All patients also received polyphenols (300 mg/d), lipoic acid (300 mg/d), carbocysteine (2.7 g/d), and vitamins A, C, and E. Lean body mass (dual energy X-ray absorptiometry and L3 computed tomography) and physical activity (6-min walk test) increased in both groups.

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HPA axis, metabolic impairment, and pediatric obesity

As published in BMC Medicine, elevated ACTH levels are associated with hypertriglyceridemia and hyperglycemia, and elevated cortisol levels are associated with hypertension and high LDL-C in obese children and adolescents (n=450).

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