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Physician Assistant - Hematology/Oncology News & Articles

The Medical Editors at MDLinx.com diligently work around the clock to provide the most current Physician Assistant medical news articles from over 2,000 peer-reviewed clinical journals. Our coverage includes over 32 specialties and 800 subspecialties, perfect for the multidisciplinary practice of today’s PAs. Topics include: everything from Anesthesiology to Women’s Health, plus Economics of Medicine, Popular Press, Teaching Hospital News, and much more. In less than 5 minutes a day, Physician Assistants can be updated with the latest published information from thousands of journals after consulting just one resource.

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Articles

Latest (17) Full Text Articles (1655)
Ranked, sorted, and summarized by MDLinx editors from the latest literature
Topics:

121 Plk1-dependent microtubule dynamics promotes androgen receptor signaling in prostate cancer The Prostate, May 13, 2013    Clinical Article

122 Anaemia and cognitive performances in the elderly: a systematic review European Journal of Neurology, May 13, 2013    Evidence Based Medicine    Review Article

123 Expression of VEGF and Semaphorin Genes Define Subgroups of Triple Negative Breast Cancer PLOS ONE, May 13, 2013    Review Article

124 Multiple-to-Multiple Relationships between MicroRNAs and Target Genes in Gastric Cancer PLOS ONE, May 13, 2013    Review Article

125 Image-directed, tissue-preserving focal therapy of prostate cancer: a feasibility study of a novel deformable MR-US registration system BJU International, May 13, 2013    Clinical Article

126 Genetic association between selected cytokine genes and glioblastoma in the Han Chinese population Full Text BMC Cancer, May 13, 2013    Clinical Article

127 Ericifolin: a novel antitumor compound from allspice that silences androgen receptor in prostate cancer Carcinogenesis, May 13, 2013    Clinical Article

128 Fried meat intake is a risk factor for lung adenocarcinoma in a prospective cohort of Chinese men and women in Singapore Carcinogenesis, May 13, 2013    Clinical Article

129 Effect of Conjugated Linoleic Acid Supplementation on Inflammatory Factors and Matrix Metalloproteinase Enzymes in Rectal Cancer Patients Undergoing Chemoradiotherapy Integrative Cancer Therapies , May 13, 2013    Clinical Article

130 Determinants of patient screen failures in Phase 1 clinical trials Investigational New Drugs, May 13, 2013    Clinical Article

131 Role of WNT7B-induced Noncanonical Pathway in Advanced Prostate Cancer Molecular Cancer Research, May 13, 2013    Clinical Article

132 Complete Necrosis of a Giant Cell Tumor with High Expression of PPARγ: A Case Report Anticancer Research, May 13, 2013

133 Current opinion on optimal treatment for colorectal cancer Expert Review of Anticancer Therapy, May 13, 2013    Review Article

134 Serious Complications Associated with Stereotactic Ablative Radiotherapy and Strategies to Mitigate the Risk Clinical Oncology, May 13, 2013    Clinical Article

135 SERPINB2 down-regulation contributes to chemoresistance in head and neck cancer Molecular Carcinogenesis, May 13, 2013    Clinical Article

136 Prohibitin-2 promotes hepatocellular carcinoma malignancy progression in hypoxia based on a label-free quantitative proteomics strategy Molecular Carcinogenesis, May 13, 2013    Clinical Article

137 Targeting IL-15 in large granular lymphocyte leukemia Expert Review of Clinical Immunology, May 13, 2013    Review Article

138 Correlation between 99mTc-HYNIC-octreotide SPECT/CT somatostatin receptor scintigraphy and pathological grading of meningioma Journal of Neuro-Oncology, May 13, 2013    Clinical Article

139 Cytoreductive surgery combined with hyperthermic intrapleural chemotherapy to treat thymoma or thymic carcinoma with pleural dissemination Full Text OncoTargets and Therapy, May 13, 2013    Clinical Article

140 Depleting NFAT1 expression inhibits the ability of invasion and migration of human lung cancer cells Cancer Cell International, May 13, 2013    Clinical Article

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Clinical Pearls in Physician Assistant

Highlights in Physician Assistant

Statins do not increase risk of malignant melanoma in postmenopausal women

In a study headed by researchers at Wayne State University involving 119,726 postmenopausal women enrolled in the Women’s Health Initiative, there were 1099 incident cases of malignant melanoma over an average follow-up of 11.6 y. At the time of enrollment, 7.4% of the participants used statins. The annualized rate of malignant melanoma in the statin users and non-users was 0.09% (HR=1.14). Thus, statin use does not increase the risk of malignant melanoma in postmenopausal women.

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Simple, safe, effective, low-cost treatment for cancer-related anorexia/cachexia syndrome

A phase III trial conducted at the University of Cagliari showed that either of two regimens were effective in the treatment of cancer-related anorexia/cachexia syndrome (CACS). Sixty patients were randomized to receive one of the following treatment interventions for 4 months: 1) L-carnitine (4 g/d) + celecoxib (300 mg/d); or 2) L-carnitine + celecoxib + megestrol acetate (320 mg/d). All patients also received polyphenols (300 mg/d), lipoic acid (300 mg/d), carbocysteine (2.7 g/d), and vitamins A, C, and E. Lean body mass (dual energy X-ray absorptiometry and L3 computed tomography) and physical activity (6-min walk test) increased in both groups.

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HPA axis, metabolic impairment, and pediatric obesity

As published in BMC Medicine, elevated ACTH levels are associated with hypertriglyceridemia and hyperglycemia, and elevated cortisol levels are associated with hypertension and high LDL-C in obese children and adolescents (n=450).

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