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Physician Assistant - Rheumatology News & Articles

The Medical Editors at MDLinx.com diligently work around the clock to provide the most current Physician Assistant medical news articles from over 2,000 peer-reviewed clinical journals. Our coverage includes over 32 specialties and 800 subspecialties, perfect for the multidisciplinary practice of today’s PAs. Topics include: everything from Anesthesiology to Women’s Health, plus Economics of Medicine, Popular Press, Teaching Hospital News, and much more. In less than 5 minutes a day, Physician Assistants can be updated with the latest published information from thousands of journals after consulting just one resource.

Read on to find exclusive content highly recommended by our Senior Editor, D. Scott Cunningham, MD, PhD, along with clinical pearls from the Smartest Doc , a daily quiz competition now available in 10 specialties.

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Latest (10) Full Text Articles (120)
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41 A randomised, double-blind, parallel-group study to demonstrate equivalence in efficacy and safety of CT-P13 compared with innovator infliximab when coadministered with methotrexate in patients with active rheumatoid arthritis: the PLANETRA study Annals of Rheumatic Diseases, May 21, 2013    Clinical Article

42 Similar response rates in patients with ankylosing spondylitis and non-radiographic axial spondyloarthritis after 1 year of treatment with etanercept: results from the ESTHER trial Annals of Rheumatic Diseases, May 21, 2013    Clinical Article

43 The development of candidate composite disease activity and responder indices for psoriatic arthritis (GRACE project) Annals of Rheumatic Diseases, May 21, 2013    Clinical Article

44 Cam impingement causes osteoarthritis of the hip: a nationwide prospective cohort study (CHECK) Annals of Rheumatic Diseases, May 21, 2013    Clinical Article

45 Revisiting the classification of clinical phenotypes of anti-neutrophil cytoplasmic antibody-associated vasculitis: a cluster analysis Annals of Rheumatic Diseases, May 21, 2013    Clinical Article

46 Autophagy contributes to inflammation in patients with TNFR-associated periodic syndrome (TRAPS) Annals of Rheumatic Diseases, May 21, 2013    Review Article

47 Granulocyte colony stimulating factor exacerbates antineutrophil cytoplasmic antibody vasculitis Annals of Rheumatic Diseases, May 21, 2013    Review Article

48 Muscle cell-derived factors inhibit inflammatory stimuli-induced damage in hMSC-derived chondrocytes Osteoarthritis and Cartilage , May 21, 2013    Review Article

49 Gradual strenuous running regimen predisposes to osteoarthritis due to cartilage cell death and altered levels of glycosaminoglycans Osteoarthritis and Cartilage , May 21, 2013    Review Article

50 Juvenile idiopathic arthritis: an update on current pharmacotherapy and future perspectives Expert Opinion on Pharmacotherapy, May 21, 2013    Clinical Article

51 Hypoxia-Inducible Factor: A Potential Therapeutic Target for Rheumatoid Arthritis Current Drug Targets, May 21, 2013    Clinical Article

52 MicroRNA-488 regulates zinc transporter SLC39A8/ZIP8 during pathogenesis of osteoarthritis Full Text Journal of Biomedical Science, May 21, 2013

53 Validation of methotrexate-first strategy in early poor prognosis rheumatoid arthritis: Results from a randomized, double-blind, 2-year trial Arthritis & Rheumatism, May 20, 2013    Clinical Article

54 Anti-cyclic citrullinated peptide assays differ in subjects at elevated risk for rheumatoid arthritis and subjects with established disease Arthritis & Rheumatism, May 20, 2013    Clinical Article

55 Sonographic joint assessment in rheumatoid arthritis: Associations with clinical joint assessment in remission Arthritis & Rheumatism, May 20, 2013    Clinical Article

56 Transcription factor Mohawk and the pathogenesis of human anterior cruciate ligament degradation Arthritis & Rheumatism, May 20, 2013    Review Article

57 The utility of the PedsQL Rheumatology Module as an outcome measure in juvenile fibromyalgia Arthritis Care & Research , May 20, 2013    Clinical Article

58 Premature cell senescence and T cell receptor-independent activation of CD8T cells in Juvenile Idiopathic Arthritis Arthritis & Rheumatism, May 20, 2013    Review Article

59 Clinical Features and Outcomes of Posterior Reversible Encephalopathy Syndrome in Patients with Systemic Lupus Erythematosus Arthritis Care & Research , May 20, 2013    Clinical Article

60 Elevated serum BAFF levels in patients with sarcoidosis: association with disease activity Rheumatology, May 20, 2013    Review Article

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Clinical Pearls in Physician Assistant

Highlights in Physician Assistant

Statins do not increase risk of malignant melanoma in postmenopausal women

In a study headed by researchers at Wayne State University involving 119,726 postmenopausal women enrolled in the Women’s Health Initiative, there were 1099 incident cases of malignant melanoma over an average follow-up of 11.6 y. At the time of enrollment, 7.4% of the participants used statins. The annualized rate of malignant melanoma in the statin users and non-users was 0.09% (HR=1.14). Thus, statin use does not increase the risk of malignant melanoma in postmenopausal women.

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Simple, safe, effective, low-cost treatment for cancer-related anorexia/cachexia syndrome

A phase III trial conducted at the University of Cagliari showed that either of two regimens were effective in the treatment of cancer-related anorexia/cachexia syndrome (CACS). Sixty patients were randomized to receive one of the following treatment interventions for 4 months: 1) L-carnitine (4 g/d) + celecoxib (300 mg/d); or 2) L-carnitine + celecoxib + megestrol acetate (320 mg/d). All patients also received polyphenols (300 mg/d), lipoic acid (300 mg/d), carbocysteine (2.7 g/d), and vitamins A, C, and E. Lean body mass (dual energy X-ray absorptiometry and L3 computed tomography) and physical activity (6-min walk test) increased in both groups.

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HPA axis, metabolic impairment, and pediatric obesity

As published in BMC Medicine, elevated ACTH levels are associated with hypertriglyceridemia and hyperglycemia, and elevated cortisol levels are associated with hypertension and high LDL-C in obese children and adolescents (n=450).

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