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Physician Assistant - Clinical Pharmacology News & Articles

The Medical Editors at MDLinx.com diligently work around the clock to provide the most current Physician Assistant medical news articles from over 2,000 peer-reviewed clinical journals. Our coverage includes over 32 specialties and 800 subspecialties, perfect for the multidisciplinary practice of today’s PAs. Topics include: everything from Anesthesiology to Women’s Health, plus Economics of Medicine, Popular Press, Teaching Hospital News, and much more. In less than 5 minutes a day, Physician Assistants can be updated with the latest published information from thousands of journals after consulting just one resource.

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Latest (10) Full Text Articles (899)
Ranked, sorted, and summarized by MDLinx editors from the latest literature
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1 Triple Therapy With Aspirin, Prasugrel, and Vitamin K Antagonists in Patients With Drug-Eluting Stent Implantation and an Indication for Oral Anticoagulation JACC - Journal of the American College of Cardiology, May 20, 2013    Clinical Article

2 Adalimumab in active ulcerative colitis: A real-life observational study Digestive and Liver Diseases, May 20, 2013    Clinical Article

3 Risk of hypertension in cancer patients treated with sorafenib: an updated systematic review and meta-analysis Journal of Human Hypertension, May 20, 2013    Evidence Based Medicine    Review Article    Clinical Article

4 Liraglutide suppresses postprandial triglyceride and apolipoprotein B48 elevations after a fat-rich meal in patients with type 2 diabetes: A randomized, double-blind, placebo-controlled, crossover trial Diabetes, Obesity and Metabolism, May 20, 2013    Clinical Article

5 Comparing nilotinib with dasatinib as second-line therapies in patients with chronic myelogenous leukemia resistant or intolerant to imatinib a retrospective chart review analysis Current Medical Research and Opinion, May 20, 2013    Review Article

6 A 6 month, prospective, observational study of PDE5 inhibitor treatment persistence and adherence in Latin American men with erectile dysfunction Current Medical Research and Opinion, May 20, 2013    Clinical Article

7 Effect of Formoterol on Eosinophil Trans-Basement Membrane Migration Induced by Interleukin-8-Stimulated Neutrophils International Archives of Allergy and Immunology, May 20, 2013    Clinical Article

8 The Effect of the Endothelin-1 Receptor Antagonist, Bosentan, on Patients with Poorly Controlled Asthma: A 17-week, Double-Blind, Placebo-Controlled Crossover Pilot Study Journal of Asthma, May 20, 2013    Clinical Article

9 Gemcitabine, oxaliplatin and dexamethasone as salvage treatment for elderly patients with refractory and relapsed peripheral T-cell lymphoma Leukemia and Lymphoma, May 20, 2013    Clinical Article

10 Esomeprazole and aspirin fixed combination for the prevention of cardiovascular events Full Text Vascular Health and Risk Management, May 20, 2013    Clinical Article

Prior Articles

11 Targeted use of heparin, heparinoids, or low-molecular-weight heparin to improve outcome after acute ischaemic stroke: an individual patient data meta-analysis of randomised controlled trials The Lancet Neurology, May 17, 2013    Evidence Based Medicine    Review Article    Clinical Article

12 Cost-Effectiveness of Duloxetine in Chronic Low Back Pain: A Quebec Societal Perspective Spine, May 17, 2013    Evidence Based Medicine    Clinical Article

13 Spinal Injection Therapy for Low Back Pain JAMA, May 17, 2013    Clinical Article

14 Impact of Adding Ezetimibe to Statin to Achieve Low-Density Lipoprotein Cholesterol Goal (from the Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation [COURAGE] Trial) The American Journal of Cardiology, May 17, 2013    Clinical Article

15 A dose-ranging study of cabozantinib in men with castration-resistant prostate cancer and bone metastases Clinical Cancer Research, May 17, 2013    Clinical Article

16 Anti tumor Necrosis Factor - Alpha Adalimumab for Complex Regional Pain Syndrome Type 1 (CRPS-I): A Case Series Pain Practice, May 17, 2013    Clinical Article

17 Triple therapy with deferiprone, idebenone and riboflavin in Friedreich's ataxia – open-label trial Acta Neurologica Scandinavica, May 17, 2013    Clinical Article

18 Influence of compliance on bone mineral density changes in postmenopausal women with early breast cancer on Anastrozole Journal of Cancer Research & Clinical Oncology, May 17, 2013    Clinical Article

19 Prescription Opioids for Back Pain and Use of Medications for Erectile Dysfunction Spine, May 17, 2013    Evidence Based Medicine    Clinical Article

20 Adulterated Sexual Enhancement Supplements: More Than Mojo JAMA Internal Medicine, May 17, 2013    Review Article    Clinical Article

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Clinical Pearls in Physician Assistant

Highlights in Physician Assistant

Statins do not increase risk of malignant melanoma in postmenopausal women

In a study headed by researchers at Wayne State University involving 119,726 postmenopausal women enrolled in the Women’s Health Initiative, there were 1099 incident cases of malignant melanoma over an average follow-up of 11.6 y. At the time of enrollment, 7.4% of the participants used statins. The annualized rate of malignant melanoma in the statin users and non-users was 0.09% (HR=1.14). Thus, statin use does not increase the risk of malignant melanoma in postmenopausal women.

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Simple, safe, effective, low-cost treatment for cancer-related anorexia/cachexia syndrome

A phase III trial conducted at the University of Cagliari showed that either of two regimens were effective in the treatment of cancer-related anorexia/cachexia syndrome (CACS). Sixty patients were randomized to receive one of the following treatment interventions for 4 months: 1) L-carnitine (4 g/d) + celecoxib (300 mg/d); or 2) L-carnitine + celecoxib + megestrol acetate (320 mg/d). All patients also received polyphenols (300 mg/d), lipoic acid (300 mg/d), carbocysteine (2.7 g/d), and vitamins A, C, and E. Lean body mass (dual energy X-ray absorptiometry and L3 computed tomography) and physical activity (6-min walk test) increased in both groups.

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HPA axis, metabolic impairment, and pediatric obesity

As published in BMC Medicine, elevated ACTH levels are associated with hypertriglyceridemia and hyperglycemia, and elevated cortisol levels are associated with hypertension and high LDL-C in obese children and adolescents (n=450).

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