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Physician Assistant - Clinical Pharmacology News & Articles

The Medical Editors at MDLinx.com diligently work around the clock to provide the most current Physician Assistant medical news articles from over 2,000 peer-reviewed clinical journals. Our coverage includes over 32 specialties and 800 subspecialties, perfect for the multidisciplinary practice of today’s PAs. Topics include: everything from Anesthesiology to Women’s Health, plus Economics of Medicine, Popular Press, Teaching Hospital News, and much more. In less than 5 minutes a day, Physician Assistants can be updated with the latest published information from thousands of journals after consulting just one resource.

Read on to find exclusive content highly recommended by our Senior Editor, D. Scott Cunningham, MD, PhD, along with clinical pearls from the Smartest Doc , a daily quiz competition now available in 10 specialties.

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Articles

Latest (15) Full Text Articles (899)
Ranked, sorted, and summarized by MDLinx editors from the latest literature
Topics:

261 Patient adherence to evidence-based pharmacotherapy in systolic heart failure and the transition of follow-up from specialized heart failure outpatient clinics to primary care European Journal of Heart Failure, May 30, 2013    Evidence Based Medicine    Clinical Article

262 Haemodynamic effects, safety, and pharmacokinetics of human stresscopin in heart failure with reduced ejection fraction European Journal of Heart Failure, May 30, 2013    Clinical Article

263 Impact of bosentan on exercise capacity in adults after the Fontan procedure: a randomized controlled trial European Journal of Heart Failure, May 30, 2013    Clinical Article

264 Nomogram for predicting survival in patients with unresectable and/or metastatic urothelial cancer who are treated with cisplatin-based chemotherapy Cancer, May 30, 2013    Clinical Article

265 Onabotulinumtoxina for the treatment of patients with overactive bladder and urinary incontinence: results of a phase 3, randomized, placebo controlled trial The Journal of Urology, May 30, 2013    Clinical Article

266 Clinical evaluation of a ten-day regimen with esomeprazole, metronidazole, amoxicillin, and clarithromycin for the eradication of Helicobacter pylori in a high clarithromycin resistance area Helicobacter, May 30, 2013    Clinical Article

267 Benzodiazepine over treatment in status epilepticus is related to higher need of intubation and longer hospitalization Epilepsia, May 30, 2013    Clinical Article

268 Modeling tumor growth kinetics after treatment with pazopanib or placebo in patients with renal cell carcinoma Cancer Chemotherapy and Pharmacology, May 30, 2013    Clinical Article

269 The effects of liver impairment on the pharmacokinetics of brivanib, a dual inhibitor of fibroblast growth factor receptor and vascular endothelial growth factor receptor tyrosine kinases Cancer Chemotherapy and Pharmacology, May 30, 2013    Clinical Article

270 Brentuximab vedotin does not cause clinically relevant QTc interval prolongation in patients with CD30-positive hematologic malignancies Cancer Chemotherapy and Pharmacology, May 30, 2013    Clinical Article

271 Efficacy of omalizumab in asthmatic patients with IgE levels above 700 IU/mL: a retrospective study Annals of Allergy, Asthma, and Immunology, May 30, 2013    Clinical Article

272 Efficacy of flibanserin in women with hypoactive sexual desire disorder: results from the begonia trial The Journal of Sexual Medicine, May 30, 2013    Clinical Article

273 Effects of long-term azithromycin therapy on airway oxidative stress markers in non-cystic fibrosis bronchiectasis Respirology, May 30, 2013    Clinical Article

274 The cost of schizophrenia in Japan Full Text Neuropsychiatric Disease and Treatment, May 30, 2013    Clinical Article

275 Effect of selective alpha-blocker tamsulosin on erectile function in patients with lower urinary tract symptoms due to benign prostatic hyperplasia Urology, May 30, 2013    Clinical Article

276 Cost-effectiveness of apixaban, dabigatran, rivaroxaban, and warfarin for stroke prevention in atrial fibrillation Stroke, May 29, 2013    Clinical Article

277 Long-term outcome with lenalidomide and dexamethasone therapy for newly diagnosed multiple myeloma Leukemia, May 29, 2013    Clinical Article

278 Incidence, presentation, and outcomes in patients with drug-induced liver injury in the general population of Iceland Gastroenterology, May 29, 2013    Clinical Article

279 The Global Drug Facility and its role in the market for tuberculosis drugs The Lancet, May 29, 2013    Review Article

280 Cyclo-oxygenase-2 inhibitors or nonselective NSAIDs plus gastroprotective agents: what to prescribe in daily clinical practice Alimentary Pharmacology and Therapeutics, May 29, 2013    Clinical Article

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Clinical Pearls in Physician Assistant

Highlights in Physician Assistant

Statins do not increase risk of malignant melanoma in postmenopausal women

In a study headed by researchers at Wayne State University involving 119,726 postmenopausal women enrolled in the Women’s Health Initiative, there were 1099 incident cases of malignant melanoma over an average follow-up of 11.6 y. At the time of enrollment, 7.4% of the participants used statins. The annualized rate of malignant melanoma in the statin users and non-users was 0.09% (HR=1.14). Thus, statin use does not increase the risk of malignant melanoma in postmenopausal women.

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Simple, safe, effective, low-cost treatment for cancer-related anorexia/cachexia syndrome

A phase III trial conducted at the University of Cagliari showed that either of two regimens were effective in the treatment of cancer-related anorexia/cachexia syndrome (CACS). Sixty patients were randomized to receive one of the following treatment interventions for 4 months: 1) L-carnitine (4 g/d) + celecoxib (300 mg/d); or 2) L-carnitine + celecoxib + megestrol acetate (320 mg/d). All patients also received polyphenols (300 mg/d), lipoic acid (300 mg/d), carbocysteine (2.7 g/d), and vitamins A, C, and E. Lean body mass (dual energy X-ray absorptiometry and L3 computed tomography) and physical activity (6-min walk test) increased in both groups.

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HPA axis, metabolic impairment, and pediatric obesity

As published in BMC Medicine, elevated ACTH levels are associated with hypertriglyceridemia and hyperglycemia, and elevated cortisol levels are associated with hypertension and high LDL-C in obese children and adolescents (n=450).

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Most Popular PA Articles

Last month's top read Top Articles of 2012

1 Omega-3 in Antiarrhythmic Therapy High Blood Pressure & Cardiovascular Prevention, April 16, 2013

2 Effects of rosuvastatin versus atorvastatin on small dense low-density lipoprotein: a meta-analysis of randomized trials Heart and Vessels, May 8, 2013    Evidence Based Medicine    Review Article

3 Efficacy and safety of Privigen in patients with chronic inflammatory demyelinating polyneuropathy: results of a prospective, single-arm, open-label Phase III study (the PRIMA study) Journal of the Peripheral Nervous System, May 22, 2013

4 Parental depression, maternal antidepressant use during pregnancy, and risk of autism spectrum disorders: population based case-control study British Medical Journal, April 23, 2013    Free full text

5 Low-dose propranolol and exercise capacity in postural tachycardia syndrome: A randomized study Neurology, May 13, 2013

6 Statins and lipid metabolism Current Opinion in Lipidology, May 24, 2013    Review Article

7 A Pilot Study Identifying Statin Nonadherence With Visit-to-Visit Variability of Low-Density Lipoprotein Cholesterol The American Journal of Cardiology, May 3, 2013

8 Antiplatelet drugs for polycythaemia vera and essential thrombocythaemia Cochrane Reviews, May 9, 2013    Evidence Based Medicine

9 Delayed antibiotics for respiratory infections Cochrane Reviews, May 13, 2013    Evidence Based Medicine

10 Vitamin D Levels for Preventing Acute Coronary Syndrome and Mortality: Evidence of a Non-Linear Association Journal of Clinical Endocrinology and Metabolism, March 27, 2013
Exclusive Author Commentary

11 New Oral Anticoagulants in Non-Valvular Atrial Fibrillation High Blood Pressure & Cardiovascular Prevention, May 13, 2013

12 Statins and autoimmunity Immunologic Research, April 17, 2013    Review Article

13 Aspirin: Its risks, benefits, and optimal use in preventing cardiovascular events Cleveland Clinic Journal of Medicine, May 8, 2013    Free full text

14 Targeted use of heparin, heparinoids, or low-molecular-weight heparin to improve outcome after acute ischaemic stroke: an individual patient data meta-analysis of randomised controlled trials The Lancet Neurology, May 17, 2013    Evidence Based Medicine    Review Article

Indexed Journals in Physician Assistant: Advance for Physicians Assistants, American Family Physicianmore

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