1Guidelines suggest blood thinners for more women, seniorsDuke Medicine
2In the short run, a high-fat diet may help minimize heart attack damageLoyola University Health System
3Brief Culturally adapted CBT (CaCBT) for depression: A randomized controlled trial from PakistanJournal of Affective Disorders  Clinical Article
4A personalised medicine approach for ponatinib-resistant chronic myeloid leukaemiaAnnals of Oncology  Clinical Article
5Genetic alterations in head and neck squamous cell carcinoma determined by cancer gene-targeted sequencingAnnals of Oncology  Clinical Article
6Early Tumor Shrinkage and Depth of Response predict long-term outcome in metastatic colorectal cancer patients treated with first-line chemotherapy plus bevacizumab: results from phase III TRIBE trial by the Gruppo Oncologico del Nord OvestAnnals of Oncology  Clinical Article
7Adaptation of the hepatitis B virus core protein to CD8+ T cell selection pressureHepatology  Clinical Article
8Towards a more complete understanding of the association between a hepatitis C sustained viral response and cause-specific outcomesHepatology  Clinical Article
9Heart rate variability and the risk of Parkinson's disease: The Atherosclerosis Risk in Communities (ARIC) StudyAnnals of Neurology  Clinical Article  Evidence Based Medicine
10Associations of serum adiponectin and leptin with Barrett’s esophagus (BE)Clinical Gastroenterology and Hepatology  Clinical Article
1Combating 'chemo mouth'Fred Hutchinson Cancer Research Center News
2Duke researchers lead studies on growing role of physician assistantsDuke University Health & Medicine News
3Teenager with stroke symptoms actually had Lyme diseaseAmerican College of Emergency Physicians News
4Are doctors using unnecessary tests to diagnose chronic kidney disease?Brigham and Women's Hospital
5Successful cognitive behavioral therapy in youth leads to decreased thinking about suicide, Penn Medicine study findsPenn Medicine
6Guidelines suggest blood thinners for more women, seniorsDuke Medicine
7Investigational therapy could attack cause of sickle cell crisesDuke Medicine
8Medicare slowdown at riskDartmouth-Hitchcock
9In the short run, a high-fat diet may help minimize heart attack damageLoyola University Health System
10Episodes of intense anger associated with high risk of heart attack within the next two hoursEuropean Society of Cardiology News

Show Me:

Sleep duration linked to lung cancer risk

As reported in BMC Public Health, men (age range, 42-60 years) who slept < 7 h/night or > 8 h/night are at increased risk for lung cancer. Specifically, amongst current smokers, the HR for lung cancer in men who slept < 6.5 h/night or > 8 h/night was 2.23 and 2.09, respectively. It is thought that melatonin excretion and/or low-grade inflammation account for this observation.

Psoriasis associated with NAFLD in elderly

As reported in the Journal of the American Academy for Dermatology, non-alcoholic fatty liver disease (NAFLD) is more common in patients > 55 years of age with psoriasis. The prevalence of NAFLD in patients with and without psoriasis was 46.2% and 33.3% (OR = 1.7), respectively.

Psychomotor speed predicts social function in schizophrenics

As reported in the Nordic Journal of Psychiatry, slow psychomotor speed predicts poor 5-y social function (OR=3.37) in patients with a diagnosis of schizophrenia spectrum. Global cognitive function and verbal learning ability had no association with subsequent social function.

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Clinical Pearls

Clinical Pearl from Smartest DocSoluble biomarkers are associated with response to TNF inhibitor therapy in psoriatic arthritis.

Clinical Pearl from Smartest DocDAPT for more than 3 months is associated with a lower risk of death, stroke or reinfarction.

Clinical Pearl from Smartest DocAdult migraines typically present with unilateral pain.

The Top Read Articles of 2014 are Now Available

Scouring thousands of peer-reviewed journals and popular press, Our Editors just released the Top Read Articles of the Year. See the Top Read List