Soluble TNF receptor II increased in MS patients
As reported in the Journal of Neuroimmunology, soluble tumor necrosis factor receptor II levels are increased in patients with untreated multiple sclerosis (n-161) compared to healthy controls (n=46), and the levels increased over a 2-year follow-up, but were not associated with the severity of disability.
Vildegliptin superior to glimepiride when added to metformin
As reported in Metabolism, addition of vildegliptin (50 mg bid) to metformin in T2DM patients inadequately controlled on metformin alone was superior to the addition of glimepiride (2 mg tid) to metformin. Patients on the vildegliptin + metformin regimen lost more weight, had an improved lipid profile, had increased insulin sensitivity, and decreased post-prandial lipemia and insulinemia compared to patients on the glimepiride + metformin regimen.
Pantothenic acid effective for acne
As reported in Dermatology and Therapy, a pantothenic acid-based dietary supplement for 12 weeks reduced the total lesion count, number of inflammatory lesions, and DLQI in patients with mild-to-moderate acne (n=41) compared to placebo.