Exercise training improves hemodynamic recovery to isometric exercise in obese men with type 2 diabetes but not in obese women
Kanaley JA et al. – Differences in blood pressure (BP) recovery immediately following isometric handgrip (IHG) may be attributed to gender differences in cardiovascular autonomic modulation. An improvement in these responses occurs following aerobic exercise training in obese men, but not in obese women with type 2 diabetes (T2D) which reflects a better adaptive autonomic response to exercise training.Methods
- Hemodynamic responses were measured in 22 men and women with T2D during and following a 3–min IHG test, and before and after 16 wks of aerobic exercise training.
- Women had a smaller decrease in mean arterial pressure (MAP) and systolic blood pressure (BP) during recovery from IHG (ΔMAPREC) than men pre– and post–training (P<0.05).
- Men showed a greater reduction in diastolic BP during recovery from IHG (P<0.05), and exercise training improved this response in men but not in women (men, pre–training: –13.9±1.8, post–training: –20.5±5.3mmHg vs. women, pre–training: –10.7±1.7, post–training: –4.1±4.9mmHg; P<0.05).
- Men had a greater reduction in sympathetic modulation of vasomotor tone (P<0.05), as estimated by blood pressure variability, following IHG.
- This response was accentuated after training, while this training effect was not seen in women.
- Post–training ΔMAPREC was correlated with recovery of low frequency component of the BP spectrum (ΔLFSBPrec, r=0.52, P<0.05).