Enhanced CD21 expression and shedding in chronic lymphatic leukemia: a possible pathomechanism in disease progression
International Journal of Hematology, 08/20/2012
Low HZ et al. – High sCD21 levels in the blood are positively correlated to the number of cells with high CD21 surface expression and the relative amount of CD21 expressed on the B cells. B–cell chronic lymphocytic leukemia (B–CLL) patients with swollen lymph nodes had higher amounts of CD21 high–expressing B cells, as well as CD21 low–expressing B cells, as compared to B–CLL patients without swollen lymph nodes.