miRNA expressions in rectal cancer as predictors of response to neoadjuvant chemoradiation therapy
International Journal of Colorectal Disease, 08/20/2012
Kheirelseid EAH et al. – Using microarray analysis of pretreatment formalin–fixed paraffin–embedded (FFPE) rectal cancer tissues, the authors identified for the first time a group of miRNA predictors of response to neoadjuvant CRT. This, indeed, can lead to a significant improvement in patient selection criteria and personalized rectal cancer management.