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Immunoglobulin gamma heavy chain gene with somatic hypermutation is frequently expressed in acute myeloid leukemia
Leukemia, 08/21/2012
Qiu X et al. – Although the function of the acute myeloid leukemia (AML)–derived IgG is unclear, the findings suggest that AML–derived IgG may be a novel AML–related gene that contributes to leukemogenesis and AML progression. AML–derived IgG may serve as a useful molecular marker for monitoring minimal residual disease or designing target therapy.