Implementation of Cerebral Autoregulation Into Computational Fluid Dynamics Studies of Cardiopulmonary Bypass
Artificial Organs, 08/17/2012
Kaufmann TAS et al. – Results indicate that even for full autoregulation, cerebral blood flow (CBF) is decreased during cardiopulmonary bypass (CPB). It is even lower for impaired autoregulation and hypertensive patients, demonstrating the strong impact of autoregulation on CBF. It is therefore imperative to include this mechanism into computational fluid dynamics studies. The presented model can help to improve CPB support conditions based on patient–specific autoregulation parameters.