TrkB expression at the neuromuscular junction is reduced during aging
Muscle & Nerve, 08/10/2012
Personius KE et al. – The results suggest that reduced TrkB expression during aging potentially results from reduced tyrosine kinase B (TrkB.FL) mRNA translation or increased TrkB protein turnover. Thus, maintaining adequate TrkB–signaling is a potential therapeutic tool to improve muscle function during senescence.