Reperfusion-triggered stress protein response in the myocardium is blocked by post-conditioning. Systems biology pathway analysis highlights the key role of the canonical aryl-hydrocarbon receptor pathway
European Heart Journal, 08/20/2012
Vilahur G et al. – IPost–Co improves cardiac function post–myocardial infarction and reduces reperfusion–induced cell damage by down–regulation of the AhR–signalling transduction pathway ultimately leading to infarct size reduction.