Dominance of the CD4+ T helper cell response during acute resolving hepatitis A virus infection Full Text
Journal of Experimental Medicine, 08/09/2012
Zhou Y et al. – The findings indicate a dominant role for CD4+ T cells in the termination of HAV infection and, possibly, surveillance of an intrahepatic reservoir of HAV genomes that decays slowly. Rapid contraction or failure to sustain such a CD4+ T cell response after resolution of symptoms could increase the risk of relapsing hepatitis A.