Does increasing the nodal yield improve outcomes in patients without nodal metastasis at radical cystectomy
World Journal of Urology, 07/31/2012
Rink M et al. – In this large multicenter cohort of patients with node–negative urothelial carcinoma of the bladder (UCB), higher nodal yield improved recurrence–free survival when all patients were analyzed. Patients with a high lymph node (LN) yield had the largest benefit. The lack of prognostic significance of LN yield in patients with muscle–invasive UCB or those stratified by 9 LNs removed suggests that this effect is weak.