Urologic complication in laparoscopic radical hysterectomy: Meta-analysis of 20 studies
European Journal of Cancer, 08/09/2012
Evidence Based Medicine
Hwang JH et al. – Laparoscopic radical hysterectomy is associated with a significant increased risk of intraoperative urologic complications.Methods
- Pubmed, EMBASE and Cochrane library were searched for studies published to December, 2011, supplemented by manual searches of relevant bibliographies from the retrieved articles.
- Two researchers independently extracted the data.
- Eligible studies had reported perioperative complications and a sample size of at least 10 patients.
- The search yielded 19 retrospective studies and one prospective cohort study (intraoperative urologic complication, 18 studies; postoperative urologic complication, 16 studies).
- When all studies were pooled, the odds ratio (OR) of LRH for the risk of intraoperative urologic complications compared to abdominal radical hysterectomy (ARH) was 1.97 [95% confidence interval (CI) 1.23–3.13] and the OR of LRH for postoperative complication risk compared to ARH was 1.35 [95% CI 0.84–2.16].
- In subgroup analysis, obesity and laparoscopic type (laparoscopic assisted vaginal radical hysterectomy) were associated with intraoperative urologic complications.