Mitochondrial effects of Ginkgo biloba extract
International Psychogeriatrics, 07/27/2012
Eckert A – A respiratory experiment indicated that Ginkgo biloba extract (GBE) was able to rescue Aβ–induced defects in energy metabolism, with results suggesting long–term regulatory effects on mitochondria. GBE also had a selective effect on the activities of mitochondrial enzymes that assemble the electron transport system. The flavonoids, bilobalide and some of the ginkgolides had a high protective capacity, indicating that a combination of several compounds within standardized Gingko biloba extracts contribute disproportionately for these protective effects.