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FDG PET scans as evaluation of clinical response to dendritic cell vaccination in patients with malignant melanoma
Cancer Immunology, Immunotherapy, 06/26/2012
Engell–Noerregaard L et al. – By adding positron emission tomography (PET) scans to the CT evaluation of patients treated with DC vaccines, a more detailed picture of the single lesions was found. This seems to improve the clinical evaluation of the treatment. The lack of correlation between the PET and CT scans suggests that some of the increases in target lesions seen in CT scans might be due to oedema or immune–infiltrates and not progression of the disease. Thus, further investigation into the contribution of PET scans to the evaluation of cancer immunotherapy is needed.