Fluorescence-guided surgical sampling of glioblastoma identifies phenotypically distinct tumour-initiating cell populations in the tumour mass and margin
British Journal of Cancer, 06/22/2012
Piccirillo SGM et al. – The data show that 5–aminolevulinic acid (5–ALA) does not compromise the derivation of tumour–initiating cells (TICs). It also reveals that the margin contains TICs, which are phenotypically different from those isolated from the corresponding mass.