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Retrospective Survey of Prodromal Symptoms in Dementia with Lewy Bodies: Comparison with Alzheimer’s Disease
Dementia and Geriatric Cognitive Disorders, 07/05/2012
Clinical Article
Chiba Y et al. – Paying attention to non–motor symptoms of Parkinson’s disease (PD) may help DLB diagnosis in the early stage, especially in terms of its differentiation from Alzheimer’s disease (AD).
Methods- The authors investigated the prevalence of 15 non-motor symptoms of PD at the onset of memory loss based on a standardized worksheet in 34 patients with DLB, 32 patients with Alzheimer’s disease (AD) and 30 normal controls.
- DLB patients exhibited a significantly higher prevalence of olfactory dysfunction, constipation, increased saliva and signs of rapid eye movement sleep behavior disorder at the onset of memory loss than AD patients and normal controls.