Catecholaminergic polymorphic ventricular tachycardia found in an adolescent after a methylenedioxymethamphetamine and marijuana-induced cardiac arrest
Critical Care Medicine, 06/29/2012
Diffley M et al. – Genetic testing showed a ryanodine receptor–2 mutation that was consistent with catecholaminergic polymorphic ventricular tachycardia. While an initial cardiac workup for an acute, undiagnosed arrhythmia may be negative, family history may be a simple, essential component of patient management and disease diagnosis. This case demonstrates a possible association between methylenedioxymethamphetamine, marijuana, and catecholaminergic polymorphic ventricular tachycardia. All genetic and structural arrythmogenic disorders should be considered when working up a patient with presumed toxin–induced arrhythmias.