Heme Protein and Hydroxyarginase Necessary for Biosynthesis of d-Cycloserine
Antimicrobial Agents and Chemotherapy, 06/20/2012
Kumagai T et al. – These results indicate that the dcsA gene product, DcsA, is an enzyme essential to generate NHA as a precursor in the DCS biosynthetic pathway. Spectroscopic analyses of the recombinant DcsA revealed that it is a heme protein, supporting an idea that DcsA is an enzyme catalyzing hydroxylation.