Untreated Human Infections by Trypanosoma brucei gambiense Are Not 100% Fatal Full Text
PLoS Neglected Tropical Diseases, 06/15/2012
Jamonneau V et al. – At least two alternative natural progressions of HAT to the “classic” fatal disease were identified: a progression to an apparently aparasitaemic and asymptomatic infection and a progression to an apparently spontaneous resolution of infection. They believe that recognising that trypanotolerance exists in humans is a major step forward for future research aimed at identifying human–specific defence and immune mechanisms involved in the control of T.b. gambiense infection and thus new candidate therapeutic or prophylactic targets.