Downregulation of microRNA-126 in endothelial progenitor cells from diabetes patients, impairs their functional properties, via target gene Spred-1
Journal of Molecular and Cellular Cardiology, 06/20/2012
Meng S et al. – This study provides the first evidence that miR–126 is downregulated in EPCs from diabetic patients, and impairs EPCs–mediated function via its target, Spred–1, and through Ras/ERK/VEGF and PI3K/Akt/eNOS signal pathway.



