Induction of virus-neutralizing antibodies and T cell responses by dengue virus type 1 virus-like particles prepared from Pichia pastoris Full Text
Chinese Medical Journal, 06/26/2012
Yun–xia T et al. – P. pastoris–expressed dengue virus type 1 (DENV–1) Virus–like particles (VLPs) can induce virus neutralizing antibodies and T cell responses in immunized mice. Using P. pastoris to produce VLPs offers a promising and economic strategy for dengue virus vaccine development.