Decreased IL-27 expression in association with an increased Th17 response in Vogt-Koyanagi-Harada disease
Investigative Ophthalmology & Visual Science, 06/08/2012
Wang C et al. – The present study suggests that a decreased IL–27 expression is associated with a higher Th17 response in active Vogt–Koyanagi–Harada patients, which may promote the autoimmune response observed in these patients. Manipulation of IL–27 may offer a novel target for treatment of this disease.