Syndrome of Inappropriate Secretion of Antidiuretic Hormone Associated With Angiotensin-Converting Enzyme Inhibitor Administration
Pediatric Cardiology, 06/01/2012
Murakami T et al. – The patient’s heart failure symptoms worsened, including accumulation of right pleural effusion and ascites, after the initiation of Angiotensin–converting enzyme inhibitors (ACEI’s) administration. Cessation of ACEI administration dramatically improved his symptoms. Because it is difficult to distinguish syndrome of inappropriate secretion of antidiuretic hormone (SIADH) associated with ACEI from worsening congestive heart failure, the possibility of fluid retention due to ACEI administration should always be considered when this agent is administered to patients with heart failure.