Upregulation of Low-Density Lipoprotein Receptor After Exposure to Transforming Growth Factor-β2 in Tenons Capsule Fibroblasts from Patients with Glaucoma
Journal of Ocular Pharmacology and Therapeutics, 05/25/2012
Zhang W et al. – This study shows that low–density lipoprotein receptor (LDLr) has a dose– and/or time–effect relationship with transforming growth factor–β2 in Tenon's capsule fibroblasts from glaucoma patients. The results suggest that LDLr may play an important role in wound healing and scar formation in the activated Tenon's capsule fibroblasts from patients with glaucoma.