Electroclinical biomarkers of early peripheral neurotoxicity from oxaliplatin
European Journal of Cancer Care, 05/21/2012
HUGH JCMC et al. – Vibration perception threshold (VPT) is an easily applicable and effective marker of neuropathy at low cumulative doses of oxaliplatin. Nerve excitability measures may be useful in predicting oxaliplatin–related neuropathy (ON) but motor studies do not reveal early cumulative changes following treatment with the drug.