The role of diabetes on the clinical manifestations of pulmonary tuberculosis
Tropical Medicine & International Health,  Clinical Article

Faurholt–Jepsen D et al. – Diabetes is associated with small changes in the manifestations of tuberculosis (TB), but may have little clinical significance.

Methods
  • The authors studied 1250 patients with pulmonary TB in an urban population in a cross–sectional study in Tanzania.
  • All participants were tested for diabetes and HIV co–infection, and TB culture intensity was assessed.
  • Levels of white blood cells, haemoglobin, acute phase reactants, CD4 count and HIV viral load were measured, and a qualitative morbidity questionnaire was used to identify the prevalence of disease–related symptoms.

Results
  • Tuberculosis patients with diabetes had a higher neutrophil count (B 0.5 × 109 cells/l, 95% CI 0.2; 0.9, P = 0.001) than non–diabetic TB patients.
  • Serum C–reactive protein (B 18.8 mg/l, CI 95% 8.2; 29.4, P = 0.001) and alpha–1–acid glycoprotein (B 0.2 g/l, CI 95% 0.03; 0.3, P = 0.02) were similarly higher in patients with diabetes.
  • Diabetes did not affect culture intensity or HIV status, but self–reported fever was three times higher among participants with diabetes than in those without diabetes (OR 2.9, CI 95% 1.5; 5.7, P = 0.002).

Please login or register to follow this author.
Are you sure you want to Unfollow this Author?
► Click here to access PubMed, Publisher and related articles...
<< Previous Article | Next Article >>

    Currently, there are no available articles.

Your Unread Messages in Physician Assistant

See All >> Messages include industry-sponsored communications and special communications from MDLinx

Most Popular Physician Assistant Articles

Indexed Journals in Physician Assistant: Advance for Physicians Assistants, American Family Physicianmore

Register now to view all the MDLinx contents (FREE)!

  • Stay current on the latest literature, research and clinical news
  • Get special communications and offers from MDLinx and our sponsors
  • Receive invitations to paid market research
View Samples and Register

Connect with us, stay current.

Receive the latest mecial news
updates for free via email

Sign up!

Subscribe to our free RSS feeds:

Get the latest news in your specialty automatically added to your newsreader or your personal My Yahoo!, Google, My MSN or My AOL page. Learn More

Close