Regulation of Hair Shedding by the Type 3 IP3 Receptor

Journal of Investigative Dermatology, 05/25/2012

The authors propose that hair shedding is actively controlled by the IP3R3–deficient (Itpr3–/–)/nuclear factor of activated T cells c1 (NFATc1)–dependent signaling pathway, possibly through the regulation of cytokeratin filaments in keratinocytes.

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