Potentiated Amygdala Response to Repeated Emotional Pictures in Borderline Personality Disorder
Biological Psychiatry, 05/09/2012
Hazlett EA et al. – The increased amygdala response to the repeated emotional pictures observed in Borderline personality disorder (BPD) was not observed in schizotypal patients, suggesting diagnostic specificity. This BPD–related abnormality is consistent with the well–documented clinical feature of high sensitivity to emotional stimuli with unusually strong and long–lasting reactions. The finding of a mismatch between physiological and self–report measures of emotion reactivity in BPD patients suggests they may benefit from treatments targeting emotion recognition.