Contribution of brain inflammation to neuronal cell death in neuronopathic forms of Gaucher's disease Full Text
Brain, 05/09/2012
Vitner EB et al. – The authors suggest that once a critical threshold of glucosylceramide storage is reached in neurons, a signalling cascade is triggered that activates microglia, which in turn releases inflammatory cytokines that amplify the inflammatory response, contributing to neuronal death.



