The -174G/C variant of IL6 as risk factor for mortality and technique failure in a large cohort of peritoneal dialysis patients
Nephrology Dialysis Transplantation, 05/16/2012
Verduijn M et al. – The C/C genotype of the –174G/C polymorphism was associated with an increased mortality risk in 398 Dutch incident peritoneal dialysis patients. The existence of substantial differences between the two academic replication cohorts and the discovery cohort from NECOSAD and the limited power of these cohorts prevented an independent replication of the NECOSAD findings.