Methotrexate: the pharmacology behind medical treatment for ectopic pregnancy
Clinical Obstetrics and Gynecology, 05/02/2012
Clinical Article
Stika CS – Its mechanism of action, competitive inhibition of folate–dependent steps in nucleic acid synthesis, effectively kills the rapidly dividing ectopic trophoblast. However, the same action on normal cells is the basis for many of its adverse effects.



