Decline in Infantile Hypertrophic Pyloric Stenosis in Germany in 2000–2008
De Laffolie J et al. – The infantile hypertrophic pyloric stenosis (IHPS) incidence declined by –38% nationwide. A parallel decline in SIDS displayed a different pattern in regional distribution; thus, a common cause was unlikely. The regional differences indicated that etiologic factors remained unresolved.
Data were extracted from the public report of health (Gesundheitsberichterstattung des Bundes).
The authors collected the numbers of IHPS (International Classification of Diseases, 10th Revision [ICD-10], code 40.0), SIDS (ICD-10, R95), and live births (LB; male/female) in each federal state for 2000–2008.
The IHPS incidence declined in Germany from 2000 (3.2086/1000 LB [range: 1.67–5.33]) to 2008 (2.0175/1000 LB [1.74–3.72]; P = .005).
The recorded incidence was highly variable in different federal states and over time.
The SIDS incidence also declined during the same time period (2000, median: 0.759/1000 LB [interquartile range: 0.54–1.029]; 2008, median: 0.416/1000 LB [interquartile range: 0.285–0.6485]; P = .0255).
However, the SIDS regional distribution was different from that of IHPS.
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