mdlinx mdlinx
Latest (546) Full Text Articles (11656) Article Summary

The development of anemia of inflammation during acute myocardial infarction
International Journal of Cardiology,

Steinvi A et al. – Inflammation–sensitive proteins are associated with lower hemoglobin concentrations in acute myocardial infarction (AMI) patients. Authors therefore suggest the possibility that at least part of the hemoglobin drop in AMI prior to angiography is related to the anemia of inflammation.

Methods
  • Authors have performed a cross–sectional analysis on prospectively collected data at a tertiary hospital catheterization laboratory.
  • Multi–adjusted linear regression models were fitted for hemoglobin as the dependent variable.
  • ANOVA tests were used to determine interactions between time cutoffs of the respective hemoglobin and the concentrations of two inflammatory proteins, namely C–reactive protein and fibrinogen.
  • Anemia indices were analyzed in a subgroup of 138 male AMI patients for whom frozen serum samples were available.

Results
  • Enrolled were 1017 patients (340 with unstable angina pectoris [UAP] and 677 with AMI).
  • Correlates of hemoglobin in the AMI group included age, male gender, the inflammatory proteins, as well as time from symptom onset to angiography (r2=0.47; p<0.001).
  • A significant decrease in the concentration of hemoglobin with a parallel increase in the inflammatory proteins was observed between the time cutoff from symptom onset to angiography only in the AMI group for males and females, respectively.
  • A pattern suggestive of anemia of inflammation including higher ferritin, lower transferring, lower transferrin saturation, and lower serum iron concentrations has been observed in anemic AMI patients ( all p<0.05).

Please login or register to follow this author.
Are you sure you want to Unfollow this Author?
► Click here to access PubMed, Publisher and related articles...
<< Previous Article | Next Article >>

    Currently, there are no available articles.

Your Unread Messages in Physician Assistant

See All >> Messages include industry-sponsored communications and special communications from MDLinx

Most Popular Physician Assistant Articles

Last month's top read Top Articles of 2013

Indexed Journals in Physician Assistant: Advance for Physicians Assistants, American Family Physicianmore

Other Topics in Physician Assistant

Register now to view all the MDLinx contents (FREE)!

  • Stay current on the latest literature, research and clinical news
  • Get special communications and offers from MDLinx and our sponsors
  • Receive invitations to paid market research
View Samples and Register

Stay current - Media Tool

Newsletter
RSS
Follow
Like

Receive the latest mecial news
updates for free via email

Sign up!

Subscribe to our free RSS feeds:

Get the latest news in your specialty automatically added to your newsreader or your personal My Yahoo!, Google, My MSN or My AOL page. Learn More

Close