TLR2 and TLR4 Gene Expression in Peripheral Monocytes in Nondiabetic Hypertensive Patients: The Effect of Intensive Blood Pressure-Lowering

The Journal of Clinical Hypertension, 05/08/2012

TLR4 mRNA levels in peripheral monocytes are significantly elevated in nondiabetic hypertensive patients. Intensive control of SBP results in attenuation of TLR2 and TLR4 gene expression in those patients. These findings suggest that a strict SBP target in nondiabetic hypertensive patients may offer additional benefits.

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