Assessment of right ventricular function for patients with rheumatic mitral stenosis by 64-slice multi-detector row computed tomography: comparison with magnetic resonance imaging

Chinese Medical Journal, 05/04/2012

ECG–gated 64–slice multi–detector row computed tomography (64–slice MDCT) could assess the RV function in rheumatic mitral stenosis (RMS) with high accuracy and reproducibility when compared to magnetic resonance imaging (MRI).


  • Right ventricular end–diastolic and end–systolic volumes (RV–EDV and RV–ESV), stroke volume (RV–SV), ejection fraction (RV–EF), cardiac output (RV–CO), and wall mass (RV–Mass) were measured with dedicated cardiac analysis software on 64–slice MDCT and compared with values measured with MRI in 43 consecutive patients with RMS.
  • Agreement between MRI and 64–MDCT results were compared with Bland and Altman analysis and linear regression analysis.
  • Repeated measurements were performed to determine intraobserver and interobserver variability.


  • No significant differences were revealed in calculated RV function parameters between the two methods.
  • RV–EDV, RV–ESV, RV–SV, RV–EF, RV–CO, and RV–Mass by 64–slice MDCT were similar to those by MRI (P >0.05).
  • There were good correlations (r=0.98, 0.97, 0.96, 0.96, 0.95 and 0.77, respectively) and close agreement (bias=–0.2 ml, –1.0 ml, 0.8 ml, 0.5%, 26.1 ml, and 0.5 g, respectively, P >0.05).
  • The variability in 64–slice MDCT measurements was similar to that in MRI values.

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