Pallido-ponto-nigral degeneration kindred shows severe disturbance of sleep

Annals of Neurology , 12/13/2010

The Pallido–ponto–nigral degeneration(PPND) kindred showed severe sleep disturbance. Sleep abnormalities are common in neurodegenerative illnesses, but this is the first study of sleep disorders in PPND. Unlike most neurodegenerative conditions, PPND is characterized by decreased total sleep time, increased sleep latency, and decreased sleep efficiency, without daytime hypersomnolence.

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